Alessandro Polini
EMail0832 319305 Orcid Scholar WOS Scopus |
Alessandro
Polini
Institute of Nanotechnology Researcher Nutrheff Thematic Biological validation
Research Interest and expertise in the field of nutraceuticals
and functional food
Keywords: in vitro models, organ-on-chip, microphysiological systems, microfabrication, tissue engineering
Nutraceuticals and foods of interestMy interest lies in the development of innovative in vitro systems, namely Organ-on-a-chip. These are microengineered tools that aim to replicate key units of living organs and organisms, and in particular to reproduce higher-order anatomical and functional features, i.e.: i) their 3D spatial arrangement; and ii) their physiology or physiopathology (gas/nutrient exchanges, absorption/secretion, cell-cell communication, etc.). The tools I propose are highly versatile and can be applied to the study of the effects of different nutraceuticals in vitro Fields of application The tools I propose are highly versatile and can be applied to different fields Facilities and equipments At CNR Nanotec clean room, microfabrication, biofabrication and cell culture facilities are available to develop and characterize organ-on-chip systems, by means of different fabrication (optical and soft lithography, additive manufacturing), material and biological characterization techniques. |
